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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MFSD6
All Species:
28.79
Human Site:
T495
Identified Species:
57.58
UniProt:
Q6ZSS7
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZSS7
NP_060164.3
791
88088
T495
L
S
H
V
S
E
L
T
A
Y
F
F
S
H
K
Chimpanzee
Pan troglodytes
XP_001166645
791
87868
T495
L
S
H
V
S
E
L
T
A
Y
F
F
S
H
K
Rhesus Macaque
Macaca mulatta
XP_001108155
793
88202
T497
L
S
H
V
S
E
L
T
A
Y
F
F
S
H
K
Dog
Lupus familis
XP_545567
795
87768
T499
L
S
H
V
S
E
L
T
A
Y
F
F
S
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBH5
775
86057
T498
L
S
H
V
S
E
L
T
A
Y
F
F
S
H
K
Rat
Rattus norvegicus
NP_001100381
794
87984
T498
L
S
H
V
S
E
L
T
A
Y
F
F
S
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521818
279
29754
S19
P
R
P
L
L
P
A
S
S
L
A
V
G
G
G
Chicken
Gallus gallus
XP_421837
786
86648
T500
L
S
H
V
S
E
L
T
A
Y
F
F
S
H
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LUQ4
793
88213
A506
L
S
H
V
S
E
L
A
A
Y
F
T
S
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610983
762
83293
E482
P
Q
P
H
I
G
A
E
S
K
V
F
A
Q
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_498662
630
68991
S369
Q
S
E
G
G
G
G
S
E
N
S
L
L
L
A
Sea Urchin
Strong. purpuratus
XP_787405
722
79257
F462
I
R
Y
G
S
V
L
F
L
A
W
F
A
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.1
87.3
N.A.
83.8
87.9
N.A.
26.1
77.5
N.A.
56.1
N.A.
35.5
N.A.
27
23.7
Protein Similarity:
100
99.4
98.6
91
N.A.
88.6
91.4
N.A.
29.3
84.4
N.A.
71.2
N.A.
52.2
N.A.
44.5
40.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
100
N.A.
86.6
N.A.
6.6
N.A.
6.6
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
N.A.
86.6
N.A.
20
N.A.
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
17
9
67
9
9
0
17
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
67
0
9
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
67
75
0
0
9
% F
% Gly:
0
0
0
17
9
17
9
0
0
0
0
0
9
17
9
% G
% His:
0
0
67
9
0
0
0
0
0
0
0
0
0
67
0
% H
% Ile:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
67
% K
% Leu:
67
0
0
9
9
0
75
0
9
9
0
9
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
17
0
17
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
75
0
0
75
0
0
17
17
0
9
0
67
0
0
% S
% Thr:
0
0
0
0
0
0
0
59
0
0
0
9
0
0
9
% T
% Val:
0
0
0
67
0
9
0
0
0
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
67
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _